Same (S-Adenosyl Methionine) 200mg Capsules

Regular price: $60.65 AUD
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Sale price: $60.65 AUD

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S-Adenosyl Methionine (SAMe) is one of the body's most important methyl donors, involved in over 100 biochemical reactions that support neurotransmitter synthesis, liver health, and joint tissue maintenance. NCC Health's SAMe 200mg Capsules provide double the standard 100mg dose in a single capsule - designed for those who have established their tolerance to SAMe and are working towards or maintaining a higher therapeutic intake under professional guidance.

HOW TO USE

Take once daily, or as directed by your healthcare practitioner. Your label will show your exact SAMe amount per daily serve. Take with water, juice or a smoothie and consume immediately. Do not exceed the recommended daily dose unless advised by your health professional.

INGREDIENTS

SAMe (S-adenosyl methionine) is a naturally occurring compound involved in methylation, liver detoxification and neurotransmitter production. It is commonly used to support healthy mood balance, joint comfort and liver function as part of a personalised nutrition program.

WARNINGS

Always read the label and use only as directed. Supplements should not replace a balanced diet. Not suitable for children under 18 years. If you are pregnant, breastfeeding, have been diagnosed with bipolar disorder, or are taking antidepressant or other prescription medicines, consult your doctor or pharmacist before using SAMe. If you experience mood changes, agitation or unusual symptoms, stop taking the product and seek medical advice.

STORAGE

Store below 25°C in a cool, dry place away from direct sunlight. Keep the container tightly closed and protect from moisture. Keep out of reach of children.

This product is made to order and may take up to 2-3 business days until ready to ship or collect.

SAMe 200mg Capsules - S-Adenosyl Methionine (Higher Dose)

SAMe is one of the body’s key methyl donors. It helps recycle homocysteine, supports the production of important brain chemicals and works closely with nutrients such as folate, vitamin B12 and betaine. Used under professional guidance, SAMe can provide targeted support for mood, energy and healthy detox pathways as part of your overall health plan.

Why SAMe (S-Adenosyl Methionine) 200mg Capsules?

Research into SAMe supplementation has used a wide range of daily doses, commonly between 400mg and 1600mg per day. The 200mg capsule allows those who have progressed beyond the introductory 100mg dose to consolidate their intake with fewer capsules, making a consistent daily routine easier to maintain. If you are new to SAMe, we recommend starting with our 100mg capsules and titrating with your healthcare professional before moving to this dose.

How SAMe Works

As a methyl donor, SAMe participates in the synthesis and regulation of:

Neurotransmitters — supporting serotonin, dopamine, and noradrenaline pathways involved in mood and mental clarity
Liver cell integrity — SAMe supports glutathione synthesis and healthy phospholipid metabolism in hepatic tissue
Cartilage components — SAMe contributes to proteoglycan synthesis, important for joint tissue structure

Quality & Formulation

Compounded in NCC Health's Gold Coast facility using pharmaceutical-grade SAMe tosylate. Prepared fresh in small batches with no unnecessary excipients. Take on an empty stomach for optimal absorption, ideally in the morning.

Important Considerations

Not suitable for those with bipolar disorder or those taking antidepressants (MAOIs, SSRIs, SNRIs) without medical guidance. SAMe may be energising — avoid taking late in the day. Inform your prescriber of all supplements you are taking.

About NCC Health

NCC Health is the consumer brand of National Custom Compounding, a Gold Coast-based Australian compounding pharmacy. Our SAMe capsules are made to pharmaceutical standards with full quality oversight.

Already established on SAMe? Upgrade to the 200mg capsule and simplify your daily routine.

FAQ

What does SAMe actually do in the body?

SAMe donates “methyl groups” that help switch many biochemical processes on and off, including the production of brain chemicals, joint cartilage components and substances involved in liver detoxification.

When should I take my SAMe?

Most people take SAMe in the morning, away from heavy meals, as this is when it is usually best tolerated. Follow the timing suggested by your healthcare practitioner and keep the time of day consistent.

Can SAMe be used with other ingredients in my custom formula?

Yes. SAMe is often combined with nutrients such as B-vitamins, magnesium and betaine to support methylation. Our pharmacist reviews your full ingredient list for compatibility and dose before compounding your product.

How long before I may notice any effects?

Response times vary, but many people notice changes in mood, energy or general wellbeing over 2–6 weeks of regular use. SAMe is intended for ongoing support, not an instant effect. Always check in with your practitioner about progress.

Is SAMe safe to use with my medications?

SAMe may not be suitable with some prescription medicines, especially antidepressants or medicines used for bipolar disorder. Please list all of your current medications when ordering and speak with your doctor or pharmacist before starting SAMe.

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