Same (S-Adenosyl Methionine) 100mg Capsules
- Regular price
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$76.90 AUD - Regular price
-
- Sale price
-
$76.90 AUD
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S-Adenosyl Methionine, commonly known as SAMe, is a naturally occurring compound produced in every cell of the human body. It is one of the most important methyl donors in human biochemistry - involved in over 100 metabolic reactions, including the synthesis of neurotransmitters, hormones, and the maintenance of cell membranes.
HOW TO USE
Take once daily, or as directed by your healthcare practitioner. Your label will show your exact SAMe amount per daily serve. Take with water, juice or a smoothie and consume immediately. Do not exceed the recommended daily dose unless advised by your health professional.
INGREDIENTS
SAMe (S-adenosyl methionine) is a naturally occurring compound involved in methylation, liver detoxification and neurotransmitter production. It is commonly used to support healthy mood balance, joint comfort and liver function as part of a personalised nutrition program.
WARNINGS
Always read the label and use only as directed. Supplements should not replace a balanced diet. Not suitable for children under 18 years. If you are pregnant, breastfeeding, have been diagnosed with bipolar disorder, or are taking antidepressant or other prescription medicines, consult your doctor or pharmacist before using SAMe. If you experience mood changes, agitation or unusual symptoms, stop taking the product and seek medical advice.
STORAGE
Store below 25°C in a cool, dry place away from direct sunlight. Keep the container tightly closed and protect from moisture. Keep out of reach of children.



Same (S-Adenosyl Methionine) 100mg Capsules
- Regular price
-
$76.90 AUD - Regular price
-
- Sale price
-
$76.90 AUD
SAMe 100mg Capsules - S-Adenosy- Methionine
SAMe is formed from the amino acid methionine and ATP. In this role, it donates methyl groups to molecules throughout the body:
- Brain chemistry: SAMe supports the synthesis of serotonin, dopamine, and noradrenaline, key neurotransmitters involved in mood and cognition.
- Liver function: SAMe is essential for glutathione production and supports healthy liver cell membrane integrity.
- Joint tissue: SAMe is involved in the synthesis of proteoglycans, structural components of cartilage
The 100mg Dose
NCC Health's 100mg capsules are designed for those beginning SAMe supplementation or those who prefer a lower, more flexible dose. The lower dose allows for easier titration - starting conservatively and adjusting based on response and guidance from a healthcare professional. SAMe is generally taken on an empty stomach for best absorption, ideally in the morning.
Quality & Formulation
Compounded by NCC Health's pharmacists in our Gold Coast facility using pharmaceutical-grade SAMe tosylate. Prepared fresh in small batches with minimal excipients for clean, consistent supplementation.
Important Considerations
SAMe is not suitable for everyone. Those with bipolar disorder, those taking antidepressants (including MAOIs, SSRIs, or SNRIs), or those with Parkinson's disease should speak with their doctor before use. Always inform your prescriber of all supplements you are taking.
About NCC Health
NCC Health is the consumer brand of National Custom Compounding, an Australian compounding pharmacy based on the Gold Coast. We provide precision-formulated supplements to pharmaceutical standards for health-conscious Australians.
Start with 100mg and experience the NCC Health compounding difference.
How SAMe Supports Your Methylation
SAMe is one of the body’s key methyl donors. It helps recycle homocysteine, supports the production of important brain chemicals, and works closely with nutrients such as folate, vitamin B12, and betaine. Used under professional guidance, SAMe can provide targeted support for mood, energy, and healthy detox pathways as part of your overall health plan.
FAQ
What does SAMe actually do in the body?
SAMe donates “methyl groups” that help switch many biochemical processes on and off, including the production of brain chemicals, joint cartilage components and substances involved in liver detoxification.
When should I take my SAMe?
Most people take SAMe in the morning, away from heavy meals, as this is when it is usually best tolerated. Follow the timing suggested by your healthcare practitioner and keep the time of day consistent.
Can SAMe be used with other ingredients in my custom formula?
Yes. SAMe is often combined with nutrients such as B-vitamins, magnesium and betaine to support methylation. Our pharmacist reviews your full ingredient list for compatibility and dose before compounding your product.
How long before I may notice any effects?
Response times vary, but many people notice changes in mood, energy or general wellbeing over 2–6 weeks of regular use. SAMe is intended for ongoing support, not an instant effect. Always check in with your practitioner about progress.
Is SAMe safe to use with my medications?
SAMe may not be suitable with some prescription medicines, especially antidepressants or medicines used for bipolar disorder. Please list all of your current medications when ordering and speak with your doctor or pharmacist before starting SAMe.
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